Clinics
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Randomized Controlled Trial
Effectiveness of Limberg and Karydakis flap in recurrent pilonidal sinus disease.
Sacrococcygeal pilonidal sinus is common in young men and may recur over time after surgery. We investigated whether a factor exists that can aid in the determination of the preferred technique between the early Limberg flap and Karydakis flap techniques for treating recurrent pilonidal sinus. ⋯ In this study, use of the Limberg flap was associated with lower complication rates, shorter length of hospital stay, early return to work, low pain score, high patient satisfaction and better complete healing duration. Therefore, we recommend the Limberg flap for treatment of recurrent pilonidal sinus.
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Controlled Clinical Trial
Serum interleukin-17 levels are associated with nephritis in childhood-onset systemic lupus erythematosus.
To determine the serum interleukin-17 (IL-17) levels in childhood-onset systemic lupus erythematosus patients and to evaluate the association between IL-17 and clinical manifestations, disease activity, laboratory findings and treatment. ⋯ IL-17 is increased in childhood-onset systemic lupus erythematosus and may play a role in the pathogenesis of neuropsychiatric and renal manifestations. Longitudinal studies are necessary to determine the role of IL-17 in childhood-onset systemic lupus erythematosus.
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Studies suggest an association between vitamin D deficiency and morbidity/mortality in critically ill patients. Several issues remain unexplained, including which vitamin D levels are related to morbidity and mortality and the relevance of vitamin D kinetics to clinical outcomes. We conducted this study to address the association of baseline vitamin D levels and vitamin D kinetics with morbidity and mortality in critically ill patients. ⋯ This study suggests that low vitamin D levels on ICU admission are an independent risk factor for mortality in critically ill patients. Low vitamin D levels at ICU admission may have a causal relationship with mortality and may serve as an indicator for vitamin D replacement among critically ill patients.
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The ability of the Timed Up and Go test to predict sarcopenia has not been evaluated previously. The objective of this study was to evaluate the accuracy of the Timed Up and Go test for predicting sarcopenia in elderly hospitalized patients. ⋯ The Timed Up and Go test was shown to be a predictor of sarcopenia in elderly hospitalized patients.
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Observational Study
Evaluation of oral-motor movements and facial mimic in patients with head and neck burns by a public service in Brazil.
The purpose of this study was to analyze the characteristics of oral-motor movements and facial mimic in patients with head and neck burns. ⋯ Patients with head and neck burns present significant deficits related to posture, position and mobility of the oral myofunctional structures, including facial movements.