EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
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Bioresorbable scaffolds promise to counteract late thrombosis by the absence of residual foreign material over time and the restoration of functional endothelial coverage. However, although currently available data are controversial, initial post-marketing studies have raised some concerns about the putative increased early thrombogenicity of bioresorbable scaffolds as compared to currently available second-generation drug-eluting stents. This article focuses on incidence rates, putative mechanisms and prevention strategies of scaffold thrombosis.
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Elevated filling pressures of the left atrium (LA) are associated with poorer outcomes in patients with chronic heart failure. The V-Wave is a new percutaneously implanted device intended to decrease the LA pressure by the shunting of blood from the LA to the right atrium. This report describes the first-in-man experience with the V-Wave device. ⋯ Left atrial decompression through a unidirectional left-to-right interatrial shunt represents a new concept for the treatment of patients with left ventricular failure. The present report shows the feasibility of applying this new therapy with the successful and uneventful implantation of the V-Wave device, which was associated with significant improvement in functional, quality of life and haemodynamic parameters at 90 days.