EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
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Although transcatheter aortic valve implantation (TAVI) is officially indicated for severe aortic stenosis (AS) patients at intermediate or higher surgical risk, the procedure is now increasingly being performed in patients who are at low surgical risk. Data on the benefit of TAVI in this patient population are limited. We therefore aimed to perform an updated meta-analysis of all published randomised controlled trials (RCTs) and propensity score-matched studies comparing TAVI versus surgical aortic valve replacement (SAVR) in patients at low surgical risk. ⋯ In patients who are at low surgical risk, TAVI seems to be associated with equivalent mortality up to a median follow-up of two years compared to SAVR. More data are required before TAVI can be routinely considered as an alternative to SAVR in low-risk patients.