Journal of cardiovascular medicine
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J Cardiovasc Med (Hagerstown) · Jan 2020
Multicenter StudyIs oral anticoagulation effective in preventing transcatheter aortic valve implantation failure? A propensity matched analysis of the Italian Transcatheter balloon-Expandable valve Registry study.
Early hypo-attenuated leaflet thickening after transcatheter aortic valve implantation (TAVI) has been recently described presumably reflecting thrombus apposition. Although its clinical relevance is still unknown, oral anticoagulant therapy (OAT) led to almost complete resolution. ⋯ After TAVI with Edwards Sapien valve OAT did not reduce the incidence of valve dysfunction and stroke but was responsible for mortality and bleeding increases.
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J Cardiovasc Med (Hagerstown) · Jan 2020
Observational StudyPrognostic impact of anemia according to frailty status in elderly patients with acute coronary syndromes.
Anemia is associated with poorer outcomes in patients with acute coronary syndromes (ACS), but the magnitude of this association in elderly patients remains poorly understood. No study has assessed the prognostic impact of anemia according to frailty status in this setting. ⋯ A high proportion of elderly patients with ACS have anemia, leading to a worse prognosis in the whole cohort. The association between anemia and mortality was especially significant in robust patients, whereas the poorer prognosis in frail patients was not modified by the presence of anemia.
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J Cardiovasc Med (Hagerstown) · Jan 2020
Comparative StudySpontaneous coronary artery dissection managed with a conservative or revascularization approach: a meta-analysis.
The optimal treatment approach for spontaneous coronary artery dissection (SCAD) remains unclear. ⋯ Pooled results suggest that SCAD patients initially managed with a conservative strategy may have similar in-hospital and long-term outcomes compared with those who received revascularization in the absence of ongoing ischemia or left main artery involvement. More data from prospective studies are warranted to validate these findings.