Acta physiologica

The most recent articles from: Acta Physiol (Oxf) December 2011

Acta physiologica · Dec 2011

The induction of mild hypothermia improves systolic function of the resuscitated porcine heart at no further sympathetic activation.

Mild hypothermia (MH) after cardiac arrest attenuates hypoxic brain injury and improves survival. As MH increases contractility in normal hearts, we hypothesized that MH improves cardiovascular function after cardiac arrest. ⋯ The induction of MH after cardiac resuscitation improves systolic myocardial function without further sympathetic activation. A reduced metabolism during MH outweighs a decreased CO and thereby acts favourably on systemic oxygen supply/demand balance.

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