Acta physiologica
The most recent articles from:
Acta Physiol (Oxf)
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Multicenter Study
Role of hyperinflation vs. deflation on dyspnoea in severely to extremely obese subjects.
To test the hypothesis that obese individuals may either hyperinflate or deflate the lung when exercising. In both cases breathlessness is an inescapable consequence. ⋯ We conclude that not all obese subjects had to increase end-expiratory lung volume on heavy-to-peak exercise. Changes in dyspnoea for unit changes in ventilation were similar in obese who did hyperinflate as well as in those who did not, suggesting that the increase in respiratory neural drive, associated with an increase in ventilation, is an important source of dyspnoea in obese as well as in control subjects.