European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes
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In the event of a spatial or temporal microvascular perfusion heterogeneity conventional methods are often inadequate to describe the microcirculatory changes. Our aim was to use a new formula to characterize and compare the microcirculatory reactions in the mucosa and longitudinal muscle of the rat small intestine in response to hypertonic/hyperoncotic and normotonic resuscitation strategies. ⋯ The hypertonic/hyperoncotic solution induces a considerable microcirculatory improvement in two distinct layers of the small intestine after HS. This positive effect is related to the amelioration of the intestinal microcirculatory heterogeneity.