Expert review of clinical immunology
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Expert Rev Clin Immunol · Mar 2014
EditorialThe practical role of serum allergen-specific IgE as potential biomarker for predicting responder to allergen immunotherapy.
Allergic asthma and rhinitis are characterized by IgE-mediated inflammation consequent to the exposure to a specific allergen. Therefore, IgE production may be considered the hallmark of allergy. Actually, allergen immunotherapy (AIT) is the unique causal treatment for respiratory allergy. ⋯ This issue has been the topic of several studies. Very recently, it has been preliminarly reported that a cut-off of serum specific IgE levels could define AIT-responder. However, further rigorous studies will confirm this view.