Clinical journal of the American Society of Nephrology : CJASN
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Clin J Am Soc Nephrol · Aug 2011
Multicenter Study Clinical TrialUrinary biomarkers and renal recovery in critically ill patients with renal support.
Despite significant advances in the epidemiology of acute kidney injury (AKI), prognostication remains a major clinical challenge. Unfortunately, no reliable method to predict renal recovery exists. The discovery of biomarkers to aid in clinical risk prediction for recovery after AKI would represent a significant advance over current practice. ⋯ We showed that a panel of urine biomarkers can augment clinical risk prediction for recovery after AKI.
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Clin J Am Soc Nephrol · Aug 2011
Multicenter StudyNeurocognitive functioning of children and adolescents with mild-to-moderate chronic kidney disease.
Few data exist on the neurocognitive functioning of children with mild-to-moderate chronic kidney disease (CKD). The primary objectives of this paper are (1) to determine the neurocognitive status in this population and (2) to identify sociodemographic and health-status variables associated with neurocognitive functioning. ⋯ Whereas most children with mild-to-moderate CKD have no major neurocognitive deficits, a substantial percentage did show neurocognitive dysfunction that places them at risk for poor long-term educational and occupational outcomes.