Clinical journal of the American Society of Nephrology : CJASN
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Clin J Am Soc Nephrol · Aug 2013
Serum soluble urokinase-type plasminogen activator receptor levels and idiopathic FSGS in children: a single-center report.
FSGS is the primary cause of childhood nephrotic syndrome leading to ESRD. Permeability factors, including circulating serum soluble urokinase-type plasminogen activator receptor (suPAR), have been postulated as putative causes in adults with primary FSGS. Similar results have yet to be proven in children. ⋯ On the basis of these results, circulating suPAR is unlikely the leading cause for childhood idiopathic FSGS.
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Clin J Am Soc Nephrol · Aug 2013
Impaired kidney function at hospital discharge and long-term renal and overall survival in patients who received CRRT.
Critically ill patients with AKI necessitating renal replacement therapy (RRT) have high in-hospital mortality, and survivors are at risk for kidney dysfunction at hospital discharge. The objective was to evaluate the association between impaired kidney function at hospital discharge with long-term renal and overall survival. ⋯ Most critically ill patients surviving AKI necessitating RRT have impaired kidney function at hospital discharge. An eGFR <30 ml/min per 1.73 m(2) is a strong risk factor for decreased long-term survival and poor renal survival.