Current clinical pharmacology
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Curr Clin Pharmacol · Jan 2018
Randomized Controlled Trial Clinical TrialThe Effect of Tranexamic Acid on Preventing Post-partum Hemorrhage Due to Uterine Atony: A Triple-blind Randomized Clinical Trial.
Postpartum haemorrhage (PPH) is an important cause of early maternal death which needs to be controlled. ⋯ The results of the present study showed that administrating intravenous TXA had comparable effects with prostaglandin analogue on reducing PPH in women with uterine atony and in those undergoing C section or vaginal delivery. Therefore, TXA can be used instead of prostaglandin in managing such patients.