Advances in medical sciences
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Review Meta Analysis
Association of Brain-derived neurotrophic factor gene polymorphisms with body mass index: A systematic review and meta-analysis.
Many studies with inconsistent results have assessed the association of Brain-derived neurotrophic factor (BDNF) gene polymorphisms with prevalence of obesity and overweight. This review aims to provide a summary of the literature evaluating the relation between BDNF genotype and body mass index (BMI). ⋯ This meta-analysis suggests that some polymorphisms in BDNF gene including rs925946, rs10501087, rs6265 and rs988712 can be considered as genetic determinants of obesity.