Expert review of gastroenterology & hepatology
-
Expert Rev Gastroenterol Hepatol · Sep 2013
ReviewAlteration of the intestinal microbiome: fecal microbiota transplant and probiotics for Clostridium difficile and beyond.
Clostridium difficile infection is increasingly common with a high risk of recurrence despite antibiotic treatment. In cases of recurrent C. difficile infection, fecal microbiota transplant (FMT) is a highly effective treatment option promoting the restoration of normal gut microbiota. ⋯ Probiotics have been utilized broadly for many disease processes, including gastrointestinal, cardiovascular and allergic disease settings, although with limited and inconsistent results. Multiple potential areas for research are also identified.