Expert review of gastroenterology & hepatology
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Expert Rev Gastroenterol Hepatol · Jul 2014
ReviewPrognosis and treatment of patients with acute alcoholic hepatitis.
Despite alcoholic hepatitis (AH) is the most acute manifestation of alcohol-related liver disease, its treatment remains controversial. Corticosteroids, given either as monotherapy or together with N-acetylecysteine, have been associated with a moderate short-term survival benefit in patients with severe disease. ⋯ Pentoxifylline is an effective alternative reducing the occurrence of hepatorenal syndrome. Emerging evidence supports use of liver transplantation in a strictly selected subset of corticosteroid non-responders.