Revue de stomatologie et de chirurgie maxillo-faciale
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Rev Stomatol Chir Maxillofac · Oct 1999
Review Case Reports[Oral amyloidosis and multiple myeloma. Apropos of a case and review of the literature].
We describe a case of amyloidosis with oral involvement as a complication of multiple myeloma. Through a review of the literature, the classification, the pathogenesis, the epidemiological and clinical aspects, the prognosis, the diagnosis and medical treatment of amyloidosis are discussed.
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Autoimmune bullous diseases (AIBD) are characterized by autoantibodies targeted against adhesion molecules, impairing their formation. According to localization criteria, pemphigus (intraepidermal blister and desmosomal involvement) and pemphigoid (subepidermal blister and dermoepidermal junction involvement) can be distinguished. In two-thirds of the cases, pemphigus vulgaris begins with oral lesions (mainly the buccal mucosa and palate, rarely the gingiva). ⋯ Immunoelectron microscopy or immunoblast transfer may be needed for positive diagnosis. Corticosteroids are used to treat pemphigus and dapsone is used for cicatricial pemphigoid. Immunosuppressive therapy is rarely needed.