Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology
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Arab J Gastroenterol · Jun 2017
Randomized Controlled Trial Comparative StudyTherapeutic success with bismuth-containing sequential and quadruple regimens in Helicobacter pylori eradication.
The success rate of Helicobacter pylori (H. pylori) eradication with the classical triple therapy is gradually declining. In this study, we aimed to compare and assess the efficacies of six different eradication regimens including sequential protocols. ⋯ In this study, OTMB and OA+OCMB were significantly superior to the triple therapy and succeeded to reach the eradication rate proposed by the Maastricht consensus (over 80%). These two bismuth-containing regimens could be considered for first-line therapy in the regions with high clarithromycin resistance.