International journal of laboratory hematology
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Comparative Study
Clinical and hematological characteristics of 88 patients with COVID-19.
To retrospectively analyze epidemiological, clinical and hematological characteristics of COVID-19 patients. ⋯ The NLR is valuable for differentiating and predicting patients who will become critical within 4 weeks after the onset of COVID-19.
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A hyperinflammatory environment has been a hallmark of COVID-19 infection and is thought to be a key mediator of morbidity. Elevated ferritin has been observed in many patients with COVID-19. Several retrospective studies have shown ferritin levels can be correlated and predictive of poor outcomes in COVID-19, though a rigorous analysis has been lacking. ⋯ Though many patients with COVID-19 present with hyperferritinemia, elevated ferritin levels are not accurate predictors of outcomes and do not appear to be indicative of hemophagocytic lymphohistiocytosis.