Zeitschrift für Orthopädie und Unfallchirurgie
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The aim of the present study was to evaluate a strategy for the management of accompanying osteoporosis after inpatient treatment of fragility fractures. ⋯ By use of a multifaceted osteoporosis intervention, more patients received diagnostics and therapy according to the guidelines of osteoporosis after fragility fractures. Without appropriate information, more than 60 % of the high-risk-patients did not receive adequate osteoporosis management. Future research should address barriers to appropriate osteoporosis management. Because of the chronic character of the disease and the necessity of a long-term therapy, continuous medical care and information of patients with osteoporosis is necessary to prevent subsequent fractures.
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The aim of this study was to examine the clinical results after the treatment of osteochondral defects of the knee with autologous bone grafting and matrix-supported autologous chondrocyte transplantation (ACT). ⋯ The treatment of osteochondral defects of the knee with autologous bone grafting and matrix-supported autologous chondrocyte transplantation shows promising results even for larger defects. But for a final decision about this therapy the present sample size was too small. There is a need for further long-term investigation with a larger number of patients.
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Comparative Study
[Visual circle scale (VCS)--a patient-friendly scale to measure pain compared to VAS and Likert scale].
The visual analogue scale (VAS) and Likert scale (LS) are widely used but the patients might have difficulties to work with these scales and there might be errors in calculation. The visual circle scale (VCS) is a graphic construct with a simple grading to augment the understanding and ease for calculation. ⋯ The VCS is able to measure pain comparably to the known scales (VAS, Likert scale). From the patients point of view it is the preferred scale to work with.
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This case report describes the application of periosteum-derived mesenchymal stem cells in a patient with atrophic non-union of the distal femur after correction osteotomy. While biomechanical treatment devices for various bone defects are available in abundance, biological promoters for clinical application in situations of critical bone healing are still scarce. We showed radiographically that cultivated autologous periosteal bone precursor cells on a three-dimensional matrix can promote bone healing in a defect where numerous established methods had failed to lead to consolidation. To the best of our knowledge, this is the first clinical application of in-vitro cultivated autologous periosteum-derived cells for the healing of a large bone defect in humans.