Addiction science & clinical practice
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Addict Sci Clin Pract · Jan 2020
Case ReportsCase report: Successful induction of buprenorphine/naloxone using a microdosing schedule and assertive outreach.
The requirement for moderate withdrawal prior to initiation can be a barrier to buprenorphine/naloxone induction. ⋯ A microdosing schedule can be used to induce a patient onto buprenorphine/naloxone with no apparent withdrawal; gradually reducing illicit substance use. This case report builds on previous literature, highlighting ways to minimize barriers to induction of buprenorphine/naloxone, using a microdosing schedule and assertive outreach. Given the safety profile of buprenorphine and its potential to be a lifesaving intervention, a larger study of microdosing is indicated.