International journal of gynaecology and obstetrics : the official organ of the International Federation of Gynaecology and Obstetrics
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Int J Gynaecol Obstet · Jan 2001
Comparative StudyPregnancy complicated by pre-eclampsia-eclampsia with HELLP syndrome.
To determine the incidence of, and assess the relationship between liver enzymes and platelet counts with the severity of HELLP (hemolysis elevated liver enzymes and low platelet count) syndrome, and describe incidences of serious maternal complications. ⋯ This study supports the theory that HELLP syndrome is associated with increased maternal morbidity and mortality. Our data suggest that certain subgroups of patients with class 1 HELLP syndrome ('classic or true HELLP') are at increased risk for serious maternal complications, including those with: platelet counts below 50000/microl; lactic dehydrogenase> or = 2000 IU/l; aspartate aminotranferase> or = 500 IU/l; alanine aminotransferase> or = 300 IU/l; and hematuria.