Archives of cardiovascular diseases
-
Arch Cardiovasc Dis · Nov 2013
Multicenter Study Comparative Study Observational StudyDefibrillation testing in everyday medical practice during implantable cardioverter defibrillator implantation in France: analysis from the LEADER registry.
Defibrillation testing (DT) is usually performed during implantable cardioverter defibrillator (ICD) implantation. ⋯ In this study, more than 10% of ICD patients were implanted without VF induction. Untested patients appeared to be sicker than tested patients, with a more severe long-term outcome, but without any difference in mortality due to arrhythmic events.
-
Arch Cardiovasc Dis · Nov 2013
Multicenter StudySignificance of atypical symptoms for the diagnosis and management of myocardial infarction in elderly patients admitted to emergency departments.
Few recent studies have examined the characteristics of ST-segment elevation myocardial infarction (STEMI) among elderly patients managed in emergency departments (EDs). ⋯ Atypical clinical symptoms of STEMI are common and severe among elderly patients in EDs. Thus, rapid provision of an electrocardiogram to all elderly patients admitted to the ED is essential, even in the absence of cardiovascular symptoms.
-
Arch Cardiovasc Dis · Nov 2013
Comparative StudyImpact of initial clinical presentation on clopidogrel low response.
Large interindividual variability exists in clopidogrel response. Clopidogrel low response correlates with poor prognosis after percutaneous coronary intervention. Some authors also suggest intraindividual variability over time. ⋯ Our study confirms that initial clinical presentation, especially ACS, is a strong predictor of clopidogrel low response; this suggests that the evolution of coronary artery disease for one patient influences the clopidogrel response over time. These results are in accordance with recent trials showing a benefit for more aggressive antiplatelet therapy in ACS patients.
-
Arch Cardiovasc Dis · Nov 2013
Comparative StudySafety and effectiveness of drug-eluting stents versus bare-metal stents in elderly patients with small coronary vessel disease.
Drug-eluting stents (DES) are more effective than bare-metal stents (BMS) in small coronary vessel disease. Whether this is true in elderly patients, it is unclear, as frailty and a high rate of comorbidities could increase the rate of DES-related complications. ⋯ In this retrospective, non-randomized analysis of the treatment of small vessel disease in elderly patients, DES were as safe and more effective than BMS with a significant reduction in TVR.