CNS neuroscience & therapeutics
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Meta Analysis
Effects of intravenous and intrathecal dexmedetomidine in spinal anesthesia: a meta-analysis.
To assess the effects of dexmedetomidine on the duration of sensory and motor block, postoperative analgesia, hypotension, bradycardia, and side effects in patients undergoing spinal anesthesia. ⋯ This meta-analysis has shown that dexmedetomidine prolonged the duration of spinal anesthesia and improved postoperative analgesia and did not increase the incidence of hypotension and adverse events, but needs more atropine to reverse bradycardia.