Klinische Monatsblätter für Augenheilkunde
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Klin Monbl Augenheilkd · Dec 2017
Review[Healthcare Research into Anti-VEGF Therapy: Selection and Methodological Precautions].
Health care research has emerged as an approach to assess and improve quality of care and patient outcomes in the real world. It also has the potential to reduce healthcare costs by providing evidence to guide healthcare decisions. Randomised controlled trials (RCTs) theoretically offer the ideal study design to support treatment decisions. ⋯ Observational studies and pragmatic trials can test new hypotheses and possible license extensions. The bearing of RCT findings on day-to-day practice can then be assessed. The data can be interpreted in a more meaningful manner by practicing clinicians if evidence is integrated from a variety of different study designs and methodologies.