Circulation. Arrhythmia and electrophysiology
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Circ Arrhythm Electrophysiol · May 2018
Minimally Invasive Delivery of Hydrogel-Encapsulated Amiodarone to the Epicardium Reduces Atrial Fibrillation.
Atrial fibrillation (AF) is the most common cardiac arrhythmia. Although treatment options for AF exist, many patients cannot be maintained in normal sinus rhythm. Amiodarone is an effective medication for AF but has limited clinical utility because of off-target tissue toxicity. ⋯ The pericardium is an underutilized therapeutic site and may be a new treatment strategy for AF and other cardiovascular diseases.