Circulation. Heart failure
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Multicenter Study Comparative Study Observational Study
Effect of estimated plasma volume reduction on renal function for acute heart failure differs between patients with preserved and reduced ejection fraction.
The prognostic relevance of plasma volume reduction (PVR) in acute heart failure patients remains unclear because of the confounding hemodynamic effect of left ventricular ejection fraction impairment on kidney function. ⋯ URL: http://www.umin.ac.jp/ctr/index-j.html. Unique identifier: UMIN000001549.
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Randomized Controlled Trial Multicenter Study Comparative Study
Effects of sildenafil on ventricular and vascular function in heart failure with preserved ejection fraction.
Early studies showed beneficial effects of phosphodiesterase 5 inhibitors on cardiovascular function in heart failure (HF) patients, but the RELAX trial observed no improvement in exercise capacity with sildenafil treatment in subjects with HF and preserved ejection fraction. ⋯ URL: http://www.clinicaltrials.gov. Unique identifier: NCT00094302.
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Randomized Controlled Trial Multicenter Study Comparative Study
Quality of anticoagulation control in preventing adverse events in patients with heart failure in sinus rhythm: Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction trial substudy.
The aim of this study is to examine the relationship between time in the therapeutic range (TTR) and clinical outcomes in heart failure patients in sinus rhythm treated with warfarin. ⋯ URL: http://www.clinicaltrials.gov. Unique identifier: NCT00041938.
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Randomized Controlled Trial Comparative Study
Left Ventricular Reverse Remodeling With Biventricular Versus Right Ventricular Pacing in Patients With Atrioventricular Block and Heart Failure in the BLOCK HF Trial.
Biventricular pacing in heart failure (HF) improves survival, relieves symptoms, and attenuates left ventricular (LV) remodeling. However, little is known about biventricular pacing in HF patients with atrioventricular block because they are typically excluded from biventricular trials. ⋯ URL: http://www.clinicaltrials.gov. Unique identifier: NCT00267098.
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Randomized Controlled Trial Multicenter Study
Regular wine consumption in chronic heart failure: impact on outcomes, quality of life, and circulating biomarkers.
Moderate, regular alcohol consumption is generally associated with a lower risk of cardiovascular events but data in patients with chronic heart failure are scarce. We evaluated the relations between wine consumption, health status, circulating biomarkers, and clinical outcomes in a large Italian population of patients with chronic heart failure enrolled in a multicenter clinical trial. ⋯ URL: http://www.clinicaltrials.gov. Unique identifier: NCT0033633.