Endoscopy
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Randomized Controlled Trial Clinical Trial
The role of pethidine in sedation for colonoscopy.
As sedation with a combination of benzodiazepines and opioids has been associated with an increased risk of serious cardiorespiratory events, it is rarely used in upper gastrointestinal endoscopy. The combination is, however, still commonly used in sedation for colonscopy and endoscopic retrograde cholangiopancreatography (ERCP). This study aimed to determine the benefits and disadvantages of adding pethidine to diazepam (Diazemuls) in the sedation for colonoscopic examinations. ⋯ Although the patients had no preference for either regime, there may be an advantage in using the combination of Diazemuls and pethidine, as there was a trend for this combination to be preferred by the colonoscopists. The combination of a benzodiazepine with an opiate should be used with caution, however, as there was a greater requirement for oxygen in the group sedated by Diazemuls and pethidine.
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The value of laparoscopy in the diagnosis of tuberculous peritonitis was determined in 32 patients diagnosed histologically as having the condition. In 27 (85%) patients the diagnosis was obtained by laparoscopy combined with peritoneal biopsy. ⋯ In the ascitic form of tuberculous peritonitis laparoscopy was a safe method which enabled a definitive diagnosis. In the fibroadhesive form of tuberculous peritonitis laparoscopy was risky and gave insufficient information, the diagnosis easily being established by laparotomy.