Scandinavian journal of infectious diseases
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Scand. J. Infect. Dis. · Jan 2009
Complicated community acquired pneumonia in children prior to the introduction of the pneumococcal conjugated vaccine.
Increasing prevalence of pleural empyema (PE) complicating community acquired pneumonia (CAP) is reported worldwide. We compared hospitalized children with PE or non-purulent pleural effusion (NP-PEF) prior to the inclusion of the pneumococcal conjugated vaccine (PCV7) in the Israeli immunization schedule. We conducted a retrospective analysis of medical files of all children <18 y of age hospitalized with either PE or NP-PEF and CAP during 1990-2002. 75 children with NP-PEF and 37 with PE were identified. ⋯ PE prevalence increased in southern Israel during the study period. Streptococcus pneumoniae (62.5% serotype 1) was the most common pathogen causing PE before the introduction of PCV7. Future introduction of PCV7 or equivalents in the immunization schedule may impact clinical presentation and epidemic trends and will require future consideration.
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Scand. J. Infect. Dis. · Jan 2009
Bacteria, biofilm and honey: a study of the effects of honey on 'planktonic' and biofilm-embedded chronic wound bacteria.
Chronically infected wounds are a costly source of suffering. An important factor in the failure of a sore to heal is the presence of multiple species of bacteria, living cooperatively in highly organized biofilms. The biofilm protects the bacteria from antibiotic therapy and the patient's immune response. ⋯ Both honeys were bactericidal against all the strains of bacteria. Biofilm was penetrated by biocidal substances in honey. Reintroduction of honey as a conventional wound treatment may help improve individual wound care, prevent invasive infections, eliminate colonization, interrupt outbreaks and thereby preserve current antibiotic stocks.
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Scand. J. Infect. Dis. · Jan 2009
Mycoplasma pneumoniae bronchiolitis in adults: clinicoradiologic features and clinical course.
The clinicoradiologic features of Mycoplasma pneumoniae bronchiolitis in adults remain unclear. 29 patients with M. pneumoniae infection were collected and classified by computed tomographic findings (bronchiolitis (n=8) and pneumonia (n=21)). M. pneumoniae bronchiolitis is not rare in adults and is clinically similar to M. pneumoniae pneumonia, despite radiographic differences.