Journal of bronchology & interventional pulmonology
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J Bronchology Interv Pulmonol · Apr 2013
Endobronchial ultrasound-guided transbronchial needle aspiration in an unselected cohort.
Endobronchial ultrasound (EBUS) with transbronchial needle aspiration (TBNA) is widely used as a diagnostic tool. The aim of this study was to evaluate the sensitivity and diagnostic accuracy of EBUS-TBNA for detecting malignant cells or sarcoidosis in mediastinal, hilar, and lobar lymph nodes. ⋯ EBUS-TBNA is a very sensitive examination in regards to carcinoma in locations accessible from the airways, but it is not suitable for the diagnosis of lymphoma. It also adds pathologic information to make the diagnosis of sarcoidosis.
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J Bronchology Interv Pulmonol · Apr 2013
Diagnostic yield of EBUS-TBNA for the evaluation of centrally located peribronchial pulmonary lesions.
The purpose of this study was to evaluate the diagnostic yield of endobronchial ultrasound with real-time-guided transbronchial needle aspiration (EBUS-TBNA), endobronchial forceps biopsy (EBBx), and 2D fluoroscopic-guided transbronchial forceps biopsy (TBLBx) for centrally located peribronchial lung lesions. ⋯ Where available, EBUS-TBNA of centrally located peribronchial lung lesions should be given a strong consideration given its high diagnostic yield.
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J Bronchology Interv Pulmonol · Apr 2013
Changes in quality of life, dyspnea scores, and lung function in lung cancer patients with airway obstruction after a therapeutic bronchoscopy.
Quality of life (QoL) has been closely linked with symptom intensity in lung cancer patients. It is therefore important to relieve respiratory distress in these severely ill patients, especially because their short life expectancy. This prospective study aimed to evaluate the impact of a therapeutic bronchoscopy on QoL, dyspnea, and lung function in patients with malignant airway obstruction. ⋯ Therapeutic bronchoscopy has a positive impact on QoL, dyspnea scale values, and lung function in patients with advanced lung cancer and airway obstruction.
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J Bronchology Interv Pulmonol · Apr 2013
Case ReportsPulmonary alveolar microlithiasis and probe-based confocal laser endomicroscopy.
Pulmonary alveolar microlithiasis (PAM) is a rare disease in which calcium-phosphate microliths accumulate within the alveolar space. We report cases of 2 siblings with PAM, presenting differently as regards the distribution and clinical severity. Immune cytologic analysis of bronchoalveolar lavage showed a CD4 alveolitis in the radiologically most affected patient, whereas the least affected had a normal bronchoalveolar lavage analysis, demonstrating the low specificity of immune cytologic lavage analysis in diagnosing familial PAM. For the first time, we describe the endoscopic findings using a probe-based confocal laser endomicroscopy.