Circulation. Cardiovascular interventions
-
Circ Cardiovasc Interv · Apr 2019
Comparative StudyComputed Tomography-Based Indexed Aortic Annulus Size to Predict Prosthesis-Patient Mismatch.
Hemodynamic performance of prostheses after transcatheter aortic valve replacement (TAVR) is generally better than after surgical aortic valve replacement (SAVR), especially in patients with a small native annulus size. However, it remains unclear whether differences are consistent for patients with a different propensity for developing prosthesis-patient mismatch (PPM), considering annulus size and body size of patients. ⋯ URL: https://www.clinicaltrials.gov . Unique identifier: NCT01586910.
-
Circ Cardiovasc Interv · Apr 2019
Multicenter Study Observational StudyInfluence of Baseline Anemia on Dual Antiplatelet Therapy Cessation and Risk of Adverse Events After Percutaneous Coronary Intervention.
Anemia is a well-recognized risk factor for both bleeding and ischemic events after percutaneous coronary intervention (PCI). We sought to determine the impact of baseline anemia on dual antiplatelet therapy (DAPT) cessation patterns ≤2 years after PCI and the subsequent risk of clinical adverse events. ⋯ Baseline anemia was associated with a significantly higher adjusted risk of MACE and major bleeding. Physicians more frequently recommend DAPT discontinuation to anemic patients during the first year, and to nonanemic patients during the second year after PCI. DAPT disruption was associated with a higher risk of MACE outcomes.