Journal of nuclear medicine : official publication, Society of Nuclear Medicine
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Comparative Study
Perfusion scintigraphy versus 256-slice CT angiography in pregnant patients suspected of pulmonary embolism: comparison of radiation risks.
One aim of the current study was to determine normalized dose data for maternal radiosensitive organs and embryo/fetus from 256-slice CT pulmonary angiography (CTPA) performed on pregnant patients suspected of having pulmonary embolism. A second aim was to provide reliable maternal and fetal doses and associated radiation cancer risk estimates from 256-slice CTPA and lung perfusion scintigraphy (LPS) for comparison. ⋯ Compared with CTPA performed with a modern wide-area CT scanner, LPS remains comparatively more dose-efficient.
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Measurement of arterial input function is a restrictive aspect for quantitative (18)F-FDG PET studies in rodents because of their small total blood volume and the related difficulties in withdrawing blood. ⋯ The vena cava time-activity curve is therefore a minimally invasive alternative for the measurement of the (18)F-FDG input function in rats and mice, without the complications associated with repetitive blood sampling.