Nature reviews. Neurology
-
Nature reviews. Neurology · May 2015
Stroke: more than meets the eye--big consequences of small strokes.
A long-term outcome analysis in patients with lacunar stroke enrolled in the Secondary Prevention of Small Subcortical Strokes trial highlights the relevance of functional disability after small-vessel strokes. These data support the emerging ‘burden of disease’ concept in individuals with cerebral microangiopathy, and the role of MRI in outcome prediction.
-
Nature reviews. Neurology · May 2015
Peripheral neuropathies: new recommendations for neuropathic pain pharmacotherapy.
A recent review and meta-analysis on pharmacotherapy for neuropathic pain provides a precise update on treatment efficacy and adverse effects. The authors offer revised evidence-based recommendations for first-line therapies and subsequent options, but we still a need to improve individual treatment decisions, including nonpharmacological therapies, in affected patients.