Arthritis care & research
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Arthritis care & research · Feb 2016
Serum uric acid & disease duration associate with frequent gout attacks but are poor at identifying such patients: A case control study.
To ascertain if readily available disease and demographic factors associate with frequent acute attacks of gout, and to find out if they can identify patients especially at risk of recurrent gout attacks. ⋯ Higher SUA and longer disease duration associate independently with frequent gout attacks, presumably because of greater crystal load. This supports early consideration of ULT for gout patients with higher SUA. However, as readily available disease and demographic factors perform poorly in identifying patients with frequent gout attacks, further research is required to ascertain the reasons underlying interpersonal variations in frequency of gout attacks. This article is protected by copyright. All rights reserved.
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Arthritis care & research · Feb 2016
Rest Pain and Movement-Evoked Pain as Unique Constructs in Hip and Knee Replacements.
There is limited information about the extent to which the association between preoperative and chronic postoperative pain is mediated via pain-on-movement or pain-at-rest. We explored these associations in patients undergoing total hip replacement (THR) and total knee replacement (TKR). ⋯ SEM illustrated the different patterns of association between measures of pain over time in patients undergoing THR and TKR for osteoarthritis. These findings highlight the importance of future work that explores the mechanisms underlying pain-on-movement and pain-at-rest.