Journal of plastic surgery and hand surgery
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J Plast Surg Hand Surg · Oct 2017
Comparative StudyPlatelet-rich plasma versus corticosteroid injections for carpal tunnel syndrome.
Platelet-rich plasma therapy has the potential to promote peripheral nerve regeneration through the autologous supply of growth factors. Therefore, this study aimed to compare the effects of platelet-rich plasma injections with the effects of corticosteroid injections in the treatment of carpal tunnel syndrome. ⋯ Platelet-rich plasma injections may be considered for the temporary symptomatic relief of mild carpal tunnel syndrome.
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J Plast Surg Hand Surg · Oct 2017
Review Meta AnalysisChemical component separation: a systematic review and meta-analysis of botulinum toxin for management of ventral hernia.
Ventral hernia represents a surgical challenge plagued by high morbidity and recurrence rates. Primary closure of challenging hernias is often prohibited by severe lateral retraction and tension of the abdominal wall musculature. Botulinum toxin injections have recently been identified as a potential pre-operative means to counteract abdominal wall tension, reduce hernia size, and facilitate fascial closure during hernia repair. This systematic review and meta-analysis reviews outcomes associated with botulinum toxin injections in the setting of ventral hernia, and demonstrates an opportunity to leverage this mainstream aesthetic product for use in abdominal wall reconstruction. ⋯ Botulinum toxin injections offer tremendous potential in ventral hernia management by reducing hernia width and lengthening abdominal wall muscles prior to repair. Although further studies are needed, there is a significant opportunity to bridge the knowledge gap in preoperative practice measures for ventral hernia risk reduction.