Chest
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OSA & COPD PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Establish an econometric probability model to serve as a complementary tool to support the diagnostic test of respiratory polygraphy to predict the probability that a patient has to suffer OSASMETHODS: It seeks to establish a Logit regression probability model with an explained variable Apnea and eight independent variables. We have performed a retrospective study in which we analyzed the different variables of 600 patients who have been subjected of a polygraphy diagnostic test. The eight apnea explanatory variables used in the study are: BMI, Epworth Scale, Snoring, Objectified Apnea pauses, Alcohol, Associated Othorhinolaryngology Pathologies, Gender and Age. Once all the data have been taken from the patients, were statistically analyzed and verified the significance of each variable in the regression model ⋯ The following authors have nothing to disclose: Antonio Jesus Dueñas Fuentes, Ana Mochón Doña, Ana Milagrosa Escribano Dueñas, Juan Antonio Piña Fernandez, Diego Gachet PaezNo Product/Research Disclosure Information.
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Lung Cancer Posters IISESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Nephrotoxicity remains major complication of drugs that are used to treat malignant disease. The most common drugs that cause nephrotoxicity are antimetobolites, alkylating agents and anthracyclins. Chemotherapeutic agents can affect the kidney with clinical manifestations that range from an asymptomatic elevation of serum creatinine to acute renal failure requiring dialysis. Our aim is to investigate the presence of predictive factors in the development of nephrotoxicity in patients receiving chemotherapy. ⋯ The following authors have nothing to disclose: Makbule Ozlem Akbay, Dilek Ernam, Erhan Ogur, Nuray Erdal, Nilgün HatabayNo Product/Research Disclosure Information.
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Tuberculosis Case Report PostersSESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: The potential complications of immune reconstitution disease during antiretroviral therapy (ART) are extremely diverse and included the unmasking form of tuberculosis. TB caused by immune reconstruction inflammatory syndrome is associated with a high mortality risk although HIV-infected patients are treated with antiretroviral agents. ⋯ Described unmasked and accelerated worsening of TB disease post-ART suggest that immune reconstitution inflammatory syndrome had contributed in both cases. Because pelvic inflammation disease is considered co-epidemic with HIV, the diagnosis of TB was delayed, the progression of TB disease was fast and severe, but the prognosis was finally a favorable one.Reference #1: Lawn SD, Meintjes G. Pathogenesis and prevention of immune reconstitution disease during antiretroviral therapy. Expert Rev. Anti Infect. Ther. 9(4), 415-430 (2011)Reference #2: Lawn SD, Wilkinson RJ, Lipman MC, Wood R. Immune reconstitution and unmasking tuberculosis during antiretroviral therapy. Am.J. respir. Crit. Care Med. 177, 680-685 (2008)DISCLOSURE: The following authors have nothing to disclose: Valerios Kortzis, Georgios Athanasiou, Ioan Arghir, Elena Dantes, Simona Cambrea, Paraschiva Postolache, Oana ArghirNo Product/Research Disclosure Information.
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COPD Comorbidity PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: To examine characteristics and related factors of abnormal heart rate recovery. Some COPD patients suffer autonomic cardiac dysfunction, having a decrease in parasympathetic activity and an increase in sympathetic activity, as reflected in the high resting heart rate, a reduced variability heart rate (HRV) and an abnormal heart rate recovery (HRR) after exercise ⋯ HRR in the 6MWT in patients with COPD could be used as an indicator of autonomic dysfunction. 6-MWT is a rapid assessment and a low cost technique to evaluate HRRDISCLOSURE: The following authors have nothing to disclose: Luis Carlos Morillo, Giorsari Quezada, Maria Enriquez, Cecilia Oropeza, Efrain Sanchez, Agustin Acuña, José Isea Dubuc6-MWT is a rapid assessment and a low cost technique to evaluate HRR.
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Cardiovascular CasesSESSION TYPE: Case ReportsPRESENTED ON: Saturday, March 22, 2014 at 04:15 PM - 05:15 PMINTRODUCTION: Primary cardiac tumors are extremely rare with a prevalence of 0.02% in pooled autopsy studies. Lymphomas involving the heart have a prevalence between 1% to 2% of primary cardiac tumors. Diagnosis usually requires tissue biopsy either by open surgical tissue resection or image-guided biopsy. We report a case of a patient who found to have a primary cardiac T-cell lymphoma (PCTCL) of the right atrium (RA) diagnosed by biopsy guided by intracardiac echocardiography (ICE). (1, 2)CASE PRESENTATION: A 66-year-old woman who presented with a 2 month history of progressive shortness of breath and orthopnea. Her ejection fraction decreased from 65% to 35% over a 4 year period. Coronary computed tomography angiography (CTA) revealed normal coronary arteries and a RA mass vs thrombus (Fig 1). A cardiac MRI with contrast was performed and the characteristic of the mass was suggestive of a lymphoma (Fig 2). Patient subsequently underwent percutaneous transcatheter biopsy of the RA mass using fluoroscopic and ICE guidance. Pathologic specimens demonstrated a T-cell lymphoma. ⋯ Patients with PCTCL typically remain asymptomatic until the mass leads to either obstruction of circulation, embolization, interference with valve function, decreased myocardial contractility or conduction disturbances. Histological diagnosis is made by biopsy and typically requires an open-chest procedure under general anesthesia. Transcatheter biopsy with transesophageal echocardiography guidance also requires general anesthesia. However, ICE imaging allows transcatheter biopsy of an intracardiac mass, especially of the right atrium. This can be made under direct visualization with conscious sedation, minimizing the risk for perforation. (3)CONCLUSIONS: Intracardiac mass biopsy using ICE is an attractive modality which provides precise localization of cardiac structures under conscious sedation. This case illustrates successful use of imaging to minimize risk in the assessment of a cardiac mass.Reference #1: Reynen K. Frequency of primary tumors of the heart. Am J Cardiol 1996;77:107-10.Reference #2: Lam KY, Dickens P, Chan AC. Tumors of the heart. A 20-year experience with a review of12,485 consecutive autopsies. Arch Pathol Lab Med 1993;117:1027-31.Reference #3: Kuppahally S.,Litwin S. Endomyocardial Biopsy of Right Atrial Angiosarcoma Guided by Intracardiac Echocardiography. Cardiology Research and Practice Volume 2010, Article ID 681726DISCLOSURE: The following authors have nothing to disclose: Ahmed Al-Badri, Sean Wilson, Chad Klinger, Carlos RuizNo Product/Research Disclosure Information.