Chest
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Randomized Controlled Trial
Intravenous magnesium sulfate for bronchiolitis: A randomized trial.
The goal of this study was to determine if IV magnesium, useful for severe pediatric asthma, reduces time to medical readiness for discharge in patients with bronchiolitis when added to supportive care. ⋯ IV magnesium did not provide benefit for patients with acute bronchiolitis and may be harmful.
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Randomized Controlled Trial Multicenter Study
Endothelial Permeability and Hemostasis in Septic Shock: Results from the ProCESS Trial.
We studied patients from the Protocolized Care in Early Septic Shock (ProCESS) trial to determine the effects of alternative resuscitation strategies on circulating markers of endothelial cell permeability and hemostasis and the association between biomarkers and mortality. ⋯ We found no relationship between different resuscitation strategies and biomarker profiles in sepsis, but we did find that elevated levels of endothelial cell biomarkers of permeability and hemostasis were associated with increased mortality.