Chest
-
Patients with pulmonary subsolid nodules (SSNs) ≤ 2 cm in diameter and a consolidation-to-tumor ratio (CTR) ≤ 0.25 have good postoperative prognoses, but their management remains controversial. ⋯ Patients with SSNs ≤ 2 cm in diameter and CTR ≤ 0.25, watchful waiting could be more appropriate than upfront surgical intervention.
-
Adaptation of the right ventricle is a key determinant of outcomes in pulmonary arterial hypertension (PAH). Despite a compelling rationale to develop targeted therapies for the right ventricle in PAH, no such treatments exist. H2-receptor antagonism is a potential myocardial-focused paradigm in heart failure. ⋯ The trial was registered at clinicaltrials.gov (NCT03554291).