Chest
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Tuberculosis PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: The efficacy of standard chemotherapy for Mycobacterium avium complex pulmonary disease (MAC-PD) is limited by poor clinical response rate, drug toxicity and side effects. When to start standard chemotherapy or which patients to treat remains undefined. In Japan, patients with MAC-PD are sometimes treated with erythromycin alone as an alternative therapy before or after standard chemotherapy to prevent disease progression. The rationale for this is that erythromycin has immunomodulatory properties independent of its antimicrobial effects. To date, however, monotherapy with erythromycin for MAC-PD is not well established. Therefore we investigated the safety, tolerability and possible clinical benefit of this treatment. ⋯ The following authors have nothing to disclose: Yukihiro Yano, Seigo Kitada, Masahide Mori, Soichiro Yokota, Ryoji MaekuraNo Product/Research Disclosure Information.
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Lung Cancer ISESSION TYPE: Slide PresentationsPRESENTED ON: Saturday, March 22, 2014 at 02:15 PM - 03:45 PMPURPOSE: This study was aimed to compare the efficacy of first-line tyrosine kinase inhibitor (TKI) followed, upon progression, by chemotherapy with the reverse sequence in patients with EGFR-mutated NSCLC in terms of overall survival (OS). ⋯ The following authors have nothing to disclose: Yiliang Zhang, Yihua Sun, Lei Wang, Ting Ye, Yunjian Pan, Haichuan Hu, Yongfu Yu, David Garfield, Haiquan ChenNo Product/Research Disclosure Information.
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Physiology/PFTs/Rehabilitation PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: To compare the effect of heliox-driven (Helium 80%: Oxygen 20%) to air-driven (Nitrogen 79%; Oxygen 21%) BD therapy on PFTs in patients with different levels of severity of airway obstructions. ⋯ The following authors have nothing to disclose: Mohamad El Khatib, Ghassan Jamaleddine, Nadim Kanj, Juliette Jibrail, Marwan Alawieh, Salah Zeineddine, Imad BouAkl, Ahmad Husari, Hassan Chami, Pierre BouKhalilNo Product/Research Disclosure Information.
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Lung Cancer Posters ISESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Tobacco smoke exposure is the main risk factor for the development of lung cancer (LC) and chronic obstructive pulmonary disease (COPD). In turn, COPD is a risk factor for the development of LC. Tobacco smoke contains a large number of free radicals, reactive oxygen species and reactive nitrogen species that increase oxidative stress. Damage to membrane lipids (lipid peroxidation) produces different volatile organic compounds (VOC) (aldehydes, carboxylic acids, etc.) that can be detected in exhaled breath. ⋯ Propanoic acid in exhaled breath samples could be used to discriminate between lung cancer patients without and with COPD. Further studies are required to confirm this hypothesis. Supported by FIS (Formación en Investigación en Salud): PI07/1116; Neumomadrid 2008 and 2012, SEPAR (Sociedad Española de Neumonología y Cirugía Torácica) 2009/881 and 2012/135CLINICAL IMPLICATIONS: New biomrkers involved in lung cancer screening and other respiratory diseases (COPD)DISCLOSURE: The following authors have nothing to disclose: Carolin Wagner, Maria Angeles Munoz, Javier Jareño, Carlos Gutierrez Ortega, Antonio Aguilar Ros, Belen Carrillo Aranda, Jose Angel Maldonado Sanz, Concepcion Civera, Luis CallolVOCs are used in the evaluation of respiratory diseases such as lung cancer, COPD.
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Pleural Case Report PostersSESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: We present the case of a 15 year old boy who presented with a spontaneous haemopneumothorax and was subsequently found to have Factor VII deficiency. ⋯ We believe this to be the first recorded case of Factor VII deficiency presenting with SHP. Management should be as for SHP with specialist advice from the haematological team.Reference #1: Hsu N-Y, Shih C-S, Hsu C-P, Chen P-R. Spontaneous Haemopneumothorax revisited: Clinical Approach and systematic review of the literature. Annals of Thoracic Surgery. 2005;80:1859-1863.Reference #2: Ali H A, Lippmann M, Mundathaje U, Khaleeq G. Spontaneous Pneumothorax - A Comprehensive Review. Chest. 2008;134:1056-1065DISCLOSURE: The following authors have nothing to disclose: Raja Dhar, Arjun RaviNo Product/Research Disclosure Information.