The journal of trauma and acute care surgery
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J Trauma Acute Care Surg · May 2012
Comparative StudyVenous thromboembolism in the elderly: the result of comorbid conditions or a consequence of injury?
Venous thromboembolism (VTE) is a common complication in trauma patients. Several risk factors have been identified that may place patients at in increased risk for VTE including preexisting medical conditions, iatrogenic factors, and injury-related factors. Advanced age has also been implicated as a risk factor for VTE. The purpose of this study was to determine the incidence and outcomes of VTE in geriatric trauma patients as well as to identify risk factors for VTE in this population. ⋯ II, prognostic study.
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J Trauma Acute Care Surg · May 2012
Comparative StudyRecreational helmet use as a predictor of noncranial injury.
The effect of helmet use in the prevention of head injury has been clearly shown. However, the relationship between helmet compliance and other bodily (noncranial) injury has not been explored, yet may have important impact on strategies for injury prevention. The purpose of this study was to examine helmet use in an injured population to evaluate its association with noncranial trauma. ⋯ III, prognostic study.
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J Trauma Acute Care Surg · May 2012
Comparative StudyInfusion of 4°C normal saline can improve the neurological outcome in a porcine model of cardiac arrest.
This study sought to investigate induction of therapeutic hypothermia using ice-cold intravenous fluid after cardiopulmonary resuscitation (CPR). The effects on temperature, hemodynamics, cognitive performance and the accompanying neurohistopathological changes, and apoptosis were assessed. ⋯ 4°C normal saline solution is a safe and effective method to reduce brain damages and prevent apoptotic cell death after cardiac arrest.
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J Trauma Acute Care Surg · May 2012
Comparative StudyAttenuating brain edema, hippocampal oxidative stress, and cognitive dysfunction in rats using hyperbaric oxygen preconditioning during simulated high-altitude exposure.
We assessed whether hyperbaric oxygen preconditioning (HBO2P) in rats induced heat shock protein (HSP)-70 and whether HSP-70 antibody (Ab) preconditioning attenuates high altitude exposure (HAE)-induced brain edema, hippocampal oxidative stress, and cognitive dysfunction. ⋯ Our results suggest that high-altitude cerebral edema, cognitive deficit, and hippocampal oxidative stress can be prevented by HSP-70-mediated HBO2P in rats.
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J Trauma Acute Care Surg · May 2012
Comparative StudyNonagenarian hip fracture: treatment and complications.
Hip fracture is a common yet serious injury sustained by the elderly patient and represents one of the major healthcare challenges today. The aim of this study was to better define the unique characteristics of treating nonagenarian peritrochanteric hip fractures and their subsequent complications during hospital stay. ⋯ III, prognostic study.