Oral surgery, oral medicine, oral pathology and oral radiology
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Oral Surg Oral Med Oral Pathol Oral Radiol · May 2013
ReviewReview and recommendations for the prevention, management, and treatment of postoperative and postdischarge nausea and vomiting.
Patients have rated severe nausea to be worse than postoperative pain. The overall incidence of postoperative nausea and vomiting (PONV) is 25%-30% and can lead to delayed discharge and unanticipated hospital admission. After outpatient surgery, the overall incidence of postdischarge nausea has been reported to be 17% and of vomiting 8%, higher than nausea and vomiting reported during the procedure or recovery. ⋯ This paper addresses the frequency, pathophysiology and patient perception of PONV and PDNV and reviews antiemetics and adjunctive medications used for the prevention, management, and treatment of PONV and PDNV. For each, the indication, mechanism of action, adverse effects, drug interactions, and implications for oral surgery and outpatient sedation are provided. Because many antiemetics are available for prevention, management, and treatment of PONV and PDNV, optimal medication choices are important for each procedure and patient.
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Oral Surg Oral Med Oral Pathol Oral Radiol · May 2013
Review Meta Analysis Comparative StudyThe effect of tranexamic acid on blood loss in orthognathic surgery: a meta-analysis of randomized controlled trials.
The objective of this article was to evaluate the efficacy of tranexamic acid on blood loss in orthognathic surgery. A meta-analysis was performed. ⋯ This meta-analysis confirms that tranexamic acid can effectively reduce intraoperative blood loss in orthognathic surgery, especially by intravenous administration. But, tranexamic acid cannot affect postoperative levels of Hb and Hct.