Contraception
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Randomized Controlled Trial
Diclofenac plus lidocaine gel for pain relief during intrauterine device insertion. A randomized, double-blinded, placebo-controlled study.
To determine the effectiveness of diclofenac potassium combined with 2% lidocaine gel in reducing the pain of intrauterine device (IUD) insertion. ⋯ Although we found a statistically significant lowering of pain scores with pretreatment with diclofenac potassium and lidocaine gel in parous women having copper IUD placement, the reduction is not clinically relevant. These findings may be more relevant for nulliparous women who experience more pain than parous women with IUD insertion and support studies of diclofenac potassium and lidocaine gel in this population.
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Randomized Controlled Trial
The effect of sevoflurane on interventions for blood loss during dilation and evacuation procedures at 18-24 weeks of gestation: a randomized controlled trial.
The objective was to evaluate whether the use of sevoflurane during general anesthesia for dilation and evacuation (D&E) procedures increases the frequency of interventions to treat excess bleeding. ⋯ In this randomized, double-blinded, placebo-controlled trial, sevoflurane did not significantly increase the risk of intervention for bleeding during D&Es. However, this agent should be used with caution as an anesthetic for surgical abortions.
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Randomized Controlled Trial
Adjunct mifepristone for cervical preparation prior to dilation and evacuation: a randomized trial.
The objective was to investigate mifepristone as a potential adjunct to cervical preparation for surgical abortion after 19 weeks of gestation, with the aim of improving procedure access, convenience and comfort. ⋯ Use of mifepristone for cervical preparation before surgical abortion after 19 weeks allows for fewer visits and fewer osmotic dilators without compromising cervical dilation or increasing procedure time.
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Randomized Controlled Trial Multicenter Study
Prophylactic ibuprofen does not improve pain with IUD insertion: a randomized trial.
To evaluate if ibuprofen 800mg reduces pain with intrauterine device (IUD) insertion among U.S. women. ⋯ Administration of ibuprofen 800mg prior to IUD insertion does not reduce pain associated with the procedure for U.S. women. Overall, nulliparous women report more pain with IUD insertion than multiparous women.
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Randomized Controlled Trial Comparative Study
Nitrous oxide for pain management of first trimester surgical abortion -- a randomized controlled pilot study.
The objective was to determine feasibility of a study comparing mean pain scores between women randomized to nitrous oxide/oxygen (NO) versus oxygen+oral analgesics for trimester surgical abortion. ⋯ The majority of eligible women agreed to participate in this study evaluating an uncommon pain control intervention.