JAMA neurology
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Randomized Controlled Trial Comparative Study
Comparison of 3 Treatment Strategies for Medication Overuse Headache: A Randomized Clinical Trial.
Medication overuse headache (MOH) is a disabling, globally prevalent disorder representing a well-known and debated clinical problem. Evidence for the most effective treatment strategy is needed. ⋯ All 3 treatment strategies were effective, but based on these findings, withdrawal therapy combined with preventive medication from the start of withdrawal is recommended as treatment for MOH.