Psychological medicine
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Psychological medicine · May 2015
Different neural and cognitive response to emotional faces in healthy monozygotic twins at risk of depression.
Negative cognitive bias and aberrant neural processing of emotional faces are trait-marks of depression. Yet it is unclear whether these changes constitute an endophenotype for depression and are also present in healthy individuals with hereditary risk for depression. ⋯ Different neural response and functional connectivity within fronto-limbic and occipito-parietal regions during emotional face processing and enhanced fear vigilance may be key endophenotypes for depression.