European journal of clinical pharmacology
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Eur. J. Clin. Pharmacol. · Apr 1998
ReviewSingle-dose dextropropoxyphene in post-operative pain: a quantitative systematic review.
To determine the analgesic efficacy and adverse effects of single-dose oral dextropropoxyphene alone and in combination with paracetamol for moderate to severe post-operative pain. ⋯ Dextropropoxyphene 65 mg plus paracetamol 650 mg has a similar analgesic efficacy to that of tramadol 100 mg but with a lower incidence of adverse effects. Ibuprofen 400 mg has a lower (better) number-needed-to-treat than both dextropropoxyphene 65 mg plus paracetamol 650 mg and tramadol 100 mg.