European journal of clinical pharmacology
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Eur. J. Clin. Pharmacol. · Feb 1999
Suspected adverse drug events requiring emergency department visits or hospital admissions.
To analyse the contribution of adverse drug events (ADEs) to the overall number of referrals or visits at an emergency department, to determine the proportion of more severe episodes requiring hospital admission and to characterize the different causes of drug-related visits or admissions. ⋯ The high proportion of drug therapeutic failures leading to an admission highlights the need for public education, particularly to prevent non-compliance.
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Eur. J. Clin. Pharmacol. · Feb 1999
Randomized Controlled Trial Clinical TrialTopical heparin for the treatment of acute superficial phlebitis secondary to indwelling intravenous catheter. A double-blind, randomized, placebo-controlled trial.
To assess the clinical efficacy of a topical gel containing 1000 IU x g(-1) of heparin, applied three times daily for a maximal period of 7 days to patients with acute superficial phlebitis secondary to indwelling intravenous catheter. ⋯ Topical heparin is safe and effective for the treatment of superficial phlebitis secondary to indwelling intravenous catheter.
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Eur. J. Clin. Pharmacol. · Feb 1999
Multicenter StudyUse of laxatives in institutions for the mentally retarded.
To study, in institutionalized mentally retarded patients, the prevalence of regular laxative use, and to identify its correlates. ⋯ Laxative use is frequent in institutions for the mentally retarded, with a large inter-institution variation, indicating that constipation is an important problem and underlining the need for research into cost-effective treatment.