European journal of clinical pharmacology
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Eur. J. Clin. Pharmacol. · Feb 2010
Stronger association of drug-induced progressive multifocal leukoencephalopathy (PML) with biological immunomodulating agents.
The aim of the present study was to collect and compare cases of drug-induced PML in order to contribute to the debate about the role of the underlying diseases and/or drug immunosuppression in PML occurrence. ⋯ We found a strong relationship between PML and MAbs, especially when used in autoimmune diseases. PML is becoming a crucial issue of MAbs, since they can cause severe ADRs through the imbalance of the immune system. Based on these results, patients treated with MAbs should be carefully monitored for early signs and symptoms of PML.
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Eur. J. Clin. Pharmacol. · Feb 2010
Letter Case ReportsProlonged hyperthermia from furosemide infusion--a case report.