American family physician
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Henoch-Schönlein purpura is a small vessel vasculitic disease thought to be caused by an immunoglobulin-mediated inflammatory process resulting from immune complex reaction to antigenic stimuli. It is a relatively common disease that will be encountered in the clinical practice of most family physicians. ⋯ It is classically manifested by palpable purpura on the lower extremities, abdominal pain, arthritis and renal involvement. Family physicians should be familiar with the disease's clinical manifestations and be aware of potentially serious complications that may affect long-term prognosis and management.
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American family physician · Feb 1993
ReviewRespiratory distress syndrome in the newborn: innovative therapies.
Neonatal respiratory distress syndrome affects 60,000 to 70,000 infants each year in the United States. Although the mortality rate has decreased dramatically over the past 30 years, many infants die or have sequelae from the syndrome. ⋯ Surfactant therapy should be considered the standard of care for infants with respiratory distress syndrome who require mechanical ventilation. Further investigation is needed to define the precise roles of high-frequency ventilation and extracorporeal membrane oxygenation in the management of neonates with respiratory distress syndrome.