The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Jan 1990
Comparative StudySystemic cold-induced urticaria--clinical and laboratory characterization.
Six patients are described with a history of cold-related urticaria in whom standard tests (water-immersion and ice-cube) did not induce symptoms. Only total-body cold exposure induced generalized urticaria. Systemic cold urticaria should, therefore, be included in the differential diagnosis of cold-dependent allergic disorders.