The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · May 1995
Hypersensitivity pneumonitis (extrinsic allergic alveolitis) induced by isocyanates.
Chemical-induced hypersensitivity pneumonitis has been so far rarely described. The purpose of this study was to find out whether hypersensitivity pneumonitis is a common disorder in isocyanate workers. ⋯ Occupational exposure to isocyanate vapors and aerosols induces typical hypersensitivity pneumonitis in at least 1% of the isocyanate workers with symptoms. Diphenylmethane diisocyanate was found to be the main cause of this disorder.