The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Dec 1996
Comparative StudyEffects of glucocorticoids on lymphocyte activation in patients with steroid-sensitive and steroid-resistant asthma.
Glucocorticoids are important medications used to control the airway inflammation associated with asthma. Synthetic glucocorticoids vary in their binding affinity for the glucocorticoid receptor (GCR). ⋯ These data suggest that glucocorticoids such as budesonide, by virtue of their high GCR binding affinities and greater ability to suppress lymphocyte proliferation, may therefore be beneficial in the management of difficult-to-control asthma.