The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Jun 1998
Randomized Controlled Trial Clinical TrialThe effects of monosodium glutamate in adults with asthma who perceive themselves to be monosodium glutamate-intolerant.
Many previous clinical studies of food-induced asthma suffer from inadequate baseline or control data. A statistically valid, randomized, double-blind, placebo-controlled, monosodium glutamate (MSG)-challenge protocol was developed for identifying early and late asthmatic reactions in an individual. ⋯ MSG-induced asthma was not demonstrated in this study. This study highlighted the importance of adequate baseline and control data and indicated that such a rigorous protocol for individual assessment is feasible.